Dr. Phanish Mysore
NAME Mysore Keshavmurthy Phanish Qualifications MB BS (JN Medical College, Karnataka University, India) MD (Gen Medicine, PGIMER, Chandigarh, India) MRCP (UK) CCST (Nephrology, UK) PhD (Renal Cell Biology, St George’s University of London, UK) FRCP(UK) current posts( since August 2007) • Consultant Nephrologist and transplant…
Dr. Phanish Mysore
NAME Mysore Keshavmurthy Phanish Qualifications MB BS (JN Medical College, Karnataka University, India) MD (Gen Medicine, PGIMER, Chandigarh, India) MRCP (UK) CCST (Nephrology, UK) PhD (Renal Cell Biology, St George’s University of London, UK) FRCP(UK) current posts( since August 2007) • Consultant Nephrologist and transplant physician (St Helier Hospital, Carshalton, Surrey, UK) • Honorary Consultant Nephrologist (Croydon University Hospital, Croydon, UK) • Honorary Senior Research Fellow (SW Thames Institute for Renal Research, St Helier Hospital, UK) • Honorary Senior Lecturer (St George’s University of London, UK) • Medical Director, SW Thames Institute for Renal Research, St Helier hospital Principal Clinical Interests Renal Transplantation, Kidney-Pancreas Transplantation Glomerulonephritis and Vasculitis Progression of renal disease, Diabetic Kidney Disease Principal Research Interests Renal Cell Biology- Proximal tubule cell biology, TGF-β1 signalling , CTGF, Cellular mechanisms of tubulo-interstitial fibrosis. Biomarkers in diabetic kidney disease and chronic allograft dysfunction Title of Ph D Thesis: Dissecting Pro-fibrotic TGF- β1 signalling in human proximal tubule epithelial cells. Current research projects: Basic Science • The regulation of post-transcriptional splicing of Fibronectin in human tubule cells. • The pro-fibrotic effects of connective tissue growth factor (CTGF) on human tubule cells. • The role of N Ras in renal fibrosis in in vitro and in vivo models. • Investigation of K Cadherin expression (tissue and urinary) and its correlation with IFTA (Interstitial fibrosis and tubular atrophy) in chronic allograft nephropathy. Translational • DUPDN-Development of diagnostic urinary panel for diabetic nephropathy. • Novel biomarkers in chronic allograft dysfunction.
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