
Hemodialysis
Hemodialysis uses a machine and a filter to clean your blood when your kidneys can no longer do it well enough. Most people have sessions about three times a week, at a dialysis center or at home.

Briefly about this treatment
Indications
Kidney failure (end-stage kidney disease), fluid your body cannot clear on its own, dangerous potassium or acid levels in the blood, and uremic symptoms such as nausea, itching and exhaustion that do not improve with medication or diet changes.
Risks
Low blood pressure, muscle cramps, bleeding at needle sites, infection and vascular access problems. Risks are reduced by monitoring during every session, good access care and an experienced dialysis team.
Pre-procedure
Standard blood tests, a heart and blood pressure check, and an ultrasound vein map to plan your vascular access, which is usually created weeks to months before the first session. Fasting is only needed for access surgery under anesthesia, not for routine sessions.
Follow-up
Regular blood tests (often monthly) and nephrologist reviews, with your access and blood pressure checked at every session. Long-term monitoring covers heart health, anemia, and bone and mineral balance.
What is Hemodialysis? An expert explains
Think of your kidneys as a filter that works around the clock. They remove waste, extra salt and extra water from your blood, and they keep minerals such as potassium in balance. When they can no longer do this well enough, those things build up and you start to feel unwell. Hemodialysis does the filtering from outside your body.
In practice, your blood travels through soft tubes to a machine, passes through a filter called a dialyzer, and returns to you cleaned. Inside the dialyzer, a thin membrane lets waste and extra fluid leave your blood while your blood cells stay inside. You do not feel the blood moving.
Hemodialysis does a lot, but not everything. It removes waste, controls fluid, helps with blood pressure and balances minerals. It works in sessions, not around the clock, which is why food and fluid limits matter between treatments. Healthy kidneys also help make red blood cells and activate vitamin D, and your team covers those jobs with medicines.
Signs it may be time for Hemodialysis
Signs that kidney failure is advancing build up slowly and differ from person to person. As waste and extra fluid collect in the blood (doctors call this uremia), you may notice:
- Deep tiredness that rest does not fix.
- Itchy skin, sometimes bad enough to wake you at night.
- Swelling in the hands, feet, ankles or face.
- Poor appetite, nausea or a metallic taste in the mouth.
- Shortness of breath, which can come from extra fluid in the body.
- Less urine, or urine that looks darker or foamier than usual.
- Foggy thinking, dizziness, feeling cold and trouble sleeping.
Some people feel fairly well even when their kidney function is very low. That is why doctors weigh symptoms and blood tests together rather than relying on one number.
Conditions linked to hemodialysis
Hemodialysis is mostly started for people whose kidneys have lost most of their function. These are the conditions most often behind it:
- End-Stage Renal Disease (ESRD): the kidneys can no longer clear waste and fluid well enough, so dialysis or a transplant is needed.
- Chronic Kidney Disease (CKD): a gradual, long-term loss of kidney function. In its last stage, your team starts to discuss dialysis or a transplant.
- Acute Kidney Injury (AKI): a sudden loss of kidney function, where hemodialysis may be used for a short time while the kidneys recover.
- Diabetic Nephropathy: kidney damage from years of high blood sugar, and one of the leading causes of kidney failure.
- Hypertensive Nephropathy: kidney damage from long-term high blood pressure, also a leading cause.
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When to consult a specialist
Having some of these signs does not mean you need dialysis. Many have other, treatable causes, and kidney problems caught early are often manageable. A simple blood test (creatinine and eGFR) and a urine test show how well your kidneys are working, and your family doctor can order them.
If the results are lower than expected, or you just want clarity, a kidney specialist can look at the full picture and explain your options at your own pace. If you ever have severe shortness of breath, chest pain or confusion, seek emergency care straight away. You do not have to work this out alone.
How a session works
- Check-in and weigh-in. Your weight tells your team how much fluid to remove.
- Access preparation. For a fistula or graft, two needles are placed: one carries blood out to the machine, one returns it. A catheter connects directly to the tubing.
- Blood begins to circulate. A pump gently moves your blood through soft tubing to the dialyzer.
- Filtering. In the dialyzer, blood flows along one side of a thin membrane and a cleansing fluid (dialysate) along the other. Waste and extra minerals pass into the dialysate, and extra fluid is drawn off.
- Cleaned blood returns to you. It flows back through the second needle or catheter line.
- Monitoring throughout. Staff check your blood pressure, heart rate and comfort regularly.
- Finishing up. The needles come out, light pressure is held on the site, and you are weighed again.
Benefits
Hemodialysis cannot replace a healthy kidney completely, but it takes over the most important cleaning jobs and can bring back stability and energy.
- It keeps you alive. When kidneys fail, waste and fluid build up to dangerous levels. Regular sessions remove them before that happens.
- It clears waste and extra fluid. This often eases swelling, breathlessness, nausea and itching.
- It helps control blood pressure. Removing extra fluid lowers the load on your heart and blood vessels.
- It corrects mineral balance. Dialysis lowers high potassium, which can disturb heart rhythm, and helps balance other minerals.
- Care is built in. In a center, a trained team checks you at every session. At home, you gain flexibility over your schedule.
- It can be a bridge to a transplant. Many people dialyze while they wait for a donor kidney.
Many people feel noticeably better once their routine settles, though how much depends on your overall health.
Risks & side effects
Hemodialysis has risks and trade-offs to discuss with your care team. The information below is general and based on the sources listed at the end of this page.
Low blood pressure, muscle cramps, bleeding at needle sites, infection and vascular access problems are the most common. Risks are reduced by monitoring during every session, good access care and an experienced dialysis team.
During or right after a session
- Low blood pressure: the most common problem. Removing fluid can leave you dizzy, nauseated or crampy, and your team can slow fluid removal or adjust your target weight.
- Muscle cramps: often linked to fluid and mineral shifts during treatment.
- Nausea, vomiting or headache: usually tied to changes in blood pressure.
- Bleeding at needle sites: blood thinners used during dialysis can make a site bleed a little longer.
- Tiredness: many people feel drained for a few hours afterward.
Between sessions
- Itchy skin: common, and treatable, so mention it to your team rather than putting up with it.
- Sleep problems: often linked to itching, restless legs or the session schedule.
Who it may not suit
These are general cautions, not a personal verdict. A qualified clinician must assess your full medical picture before recommending or delaying treatment.
- People with severe heart disease or very unstable blood pressure may tolerate sessions poorly, and another form of dialysis may suit them better.
- People whose veins are not suitable for a fistula may need a graft or a catheter, or a different type of dialysis.
- People who cannot safely take the blood thinners used during sessions may need a modified approach.
- Some older or frail people with several serious illnesses choose conservative care, which focuses on comfort and symptoms without dialysis, after talking it through with their team.
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What happens during & after
Most people can rest through a session and go home or back to normal activity afterward, though some feel tired for a few hours.
During. You sit or recline while the machine runs. Staff check your blood pressure, heart rate and comfort regularly, so tell them if you feel dizzy, cramped or unwell. Many people rest, read or watch something.
Right after. The needles come out, light pressure is held on the sites until bleeding stops, and you are weighed again to confirm how much fluid was removed.
The first hours. It is common to feel tired, washed out or lightheaded, sometimes called a „dialysis hangover” and most often linked to how much fluid was removed. This usually eases within a few hours. Tell your care team if it happens every session or feels severe, because your treatment plan can often be adjusted.
Possible complications
Years on hemodialysis carry some longer-term risks, and your team watches for them with regular blood tests, heart checks and access checks so problems are caught early.
- Heart and blood vessel disease: one of the main causes of serious illness and death in people on long-term dialysis, so heart health is reviewed at almost every visit.
- Infections: including bloodstream infections linked to the vascular access, which is why keeping the site clean matters.
- Malnutrition: dialysis removes some protein and nutrients along with waste, on top of appetite loss and diet limits.
- Low mood and anxiety: common among people on long-term dialysis. Support is available, so mention it early.
- Dialysis-related amyloidosis: a protein build-up that can cause joint and tendon pain, more common after many years of treatment.
- Nerve and bone changes: tingling or numbness (peripheral neuropathy) and secondary hyperparathyroidism, which affects calcium and bone health.
- Access complications: besides infection, an access can narrow or clot, and rarely cause „steal syndrome”, where too little blood reaches the hand beyond it.
These are possibilities, not predictions. Regular checks exist to catch them early.
New or severe symptoms require prompt medical advice. Do not wait for a routine appointment if you feel seriously unwell.
Recovery
Recovery on hemodialysis is less about healing and more about settling into a routine that fits your life, which most people manage within a few weeks.
- Your access: follow your team’s care instructions and keep the site clean. Report redness, swelling, fever, or a change in the buzzing you normally feel over a fistula.
- Diet and fluids: a renal dietitian will set limits for potassium, phosphorus, sodium and fluid, because dialysis does not replace everything healthy kidneys filter. See our hemodialysis diet guide.
- Work and school: many people return once they have adjusted to their schedule. Physically demanding jobs may need adapting, so ask your team about session times that fit.
- Travel: you can often dialyze away from home. Book a visiting-patient slot well in advance.
- Emotional adjustment: relief, grief, anxiety and frustration, sometimes in the same week, are all normal. Our psychology consultations connect you with counselors who know chronic illness.
- Monitoring: your team tracks lab results, weight trends and how you feel, and adjusts your schedule, fluid target or access as needed.
Specialists for Hemodialysis
Specialists linked to this treatment in the KidneyGlobal directory. Review credentials and confirm availability directly before booking.
Verified specialists

Clinics offering Hemodialysis
Verified kidney centres linked to this treatment in the KidneyGlobal directory.



Cleveland Clinic Glickman Urological & Kidney Institute
β Accredited
Mayo Clinic Kidney & Pancreas Transplant Center
β AccreditedMost Common Questions
Is hemodialysis painful?
The treatment itself is not painful. The main discomfort is the needle insertion at the start of a session, which most people compare to a routine blood draw. Ask your team about numbing options if needles worry you.
How often and how long are sessions?
Most people have about 4 hours of treatment 3 times a week at a center. Home schedules can be shorter and more frequent, and your nephrologist sets the plan that fits your body and lab results.
Do I have to change what I eat and drink?
Usually yes. Most people limit potassium, phosphorus, sodium and fluids, because dialysis does not replace everything healthy kidneys filter. A renal dietitian can build a plan around foods you actually enjoy.
Can I still work and travel?
Many people do both once they have settled into a routine. Physically demanding jobs may need adjusting, and dialysis centers worldwide can host visiting patients if you book ahead.
What is the difference between hemodialysis and peritoneal dialysis?
Hemodialysis filters your blood through a machine outside your body, usually at a center. Peritoneal dialysis uses the lining of your own abdomen as the filter and is done at home.
Will I need dialysis forever?
It depends on the cause. For kidney failure, dialysis is usually long-term or continues until a transplant. After a sudden kidney injury, it may be temporary while the kidneys recover, and your nephrologist will review this with you.
Sources
- Hemodialysis: How It Works, Types, and What to Expect.National Kidney Foundation.
- "Dialysis" β costs, work, and daily-life guidance.National Kidney Foundation.
- Living Well with Kidney Failure: Hemodialysis β patient booklet / video series.National Kidney Foundation.
- "Hemodialysis" β risks and what to expect.Mayo Clinic.
- Vascular Access for Hemodialysis.UCSF Vascular Surgery (NIDDK-sourced content).
- 2012 Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease (PDF) β dialysis-initiation criteria.Kidney Disease: Improving Global Outcomes (KDIGO).
- NG203: Chronic kidney disease β assessment and management β dialysis-initiation criteria (UK).NICE.
