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Open stone surgery (anatrophic nephrolithotomy)

Open stone surgery — most often performed as anatrophic nephrolithotomy — is a major operation that opens the kidney directly to remove a large or complex "staghorn" stone that less invasive methods can't safely clear. It's used today only when keyhole options such as PCNL, ureteroscopy or shockwave lithotripsy aren't suitable or haven't worked.

Open stone surgery (anatrophic nephrolithotomy)
Content verification
Prof. Piotr Radziszewski
Urology
Massachusetts General Hospital | Cleveland Clinic
Dr. Michael Chen
Urology
Massachusetts General Hospital | Cleveland Clinic
Updated date
09-10-2026
Reading time
8 mins
Authors
KidneyGlobal Editorial Team
Based on treatment data in this directory
2 verified specialist reviewers

Briefly about this treatment

Indications

A large staghorn stone filling the kidney's drainage system, when less invasive options — PCNL, ureteroscopy or shockwave lithotripsy — have already been tried without clearing the stone, or when kidney or ureter anatomy makes keyhole access unsafe.

Risks

Significant bleeding (occasionally needing a transfusion), infection, and risks associated with general anaesthesia. Risks are minimised by careful patient selection and experienced surgical teams.

Pre-procedure

CT imaging to map the stone, blood and urine tests, and an anaesthesia consultation (this surgery is done under general anaesthesia); some medications, including blood thinners, may need to be paused beforehand.

Follow-up

Monitoring in hospital for several days, a stent-removal visit at 1–4 weeks if a stent was placed, and follow-up imaging to confirm the kidney has healed and to watch for new stone formation.

What is Open stone surgery (anatrophic nephrolithotomy)? An expert explains

Anatrophic nephrolithotomy is a technique first described in 1968 for removing very large, branching kidney stones — called staghorn calculi — that fill much of the kidney’s internal drainage system. The surgeon opens the kidney along a naturally low-blood-vessel line (the avascular plane of Brödel), rather than cutting blindly through tissue. This lets the stone be lifted out through the middle of the kidney while limiting damage to the surrounding kidney tissue and blood supply. The kidney is temporarily cooled to protect it while blood flow is paused, the stone is removed, and the kidney is stitched back together and reconnected to its blood supply. Some centers now perform the same technique laparoscopically or robotically, which can mean a smaller incision and a shorter recovery for suitable patients.

Note: Prof. Piotr Radziszewski is listed as a specialist reviewer for this treatment.

Signs it may be time for Open stone surgery (anatrophic nephrolithotomy)

A stone being „big” isn’t, on its own, a reason for open surgery — it’s specific symptoms and anatomy together that point this way. Watch for:

  • Ongoing flank or back pain that doesn’t settle.
  • Recurring urinary tract infections.
  • Fever alongside kidney pain.
  • Blood in your urine.

On their own, these symptoms just mean it’s time for imaging and a specialist opinion — not that open surgery is the answer.

Open surgery also becomes more likely when the kidney’s own shape or structure makes keyhole access difficult. These are the conditions linked to this treatment in the directory. Your clinician decides whether treatment is appropriate using your symptoms, examination and test results.

Remember: These entries are not a diagnosis or a treatment recommendation. Discuss your symptoms and test results with a qualified clinician.

 

When to consult a specialist

Most people with kidney stones never need open surgery — it’s reserved for a small number of complex cases, so there’s no need to assume the worst if you’re reading this. A simple blood and urine test, together with imaging, is usually enough for a urologist to see what you’re dealing with and talk you through the realistic options. If you have ongoing flank pain, recurring infections, fever with kidney pain, or blood in your urine — or you already know you have a large or staghorn stone — it’s worth getting that assessment soon rather than waiting it out. [Find a specialist] to book a consultation and get a clear picture of your options.

How a session works

Before surgery: You’ll have imaging (usually a CT scan) to map the stone, blood and urine tests, and a discussion of anaesthesia (this is done under general anaesthesia). Your surgeon will review any medications that need to be paused beforehand, including blood thinners.

During surgery:

  1. A flank incision is made and the kidney is carefully freed from surrounding tissue.
  2. The main blood vessel to the kidney is identified, and the artery supplying the back portion of the kidney is temporarily clamped.
  3. The kidney is cooled (often with sterile ice slush) to protect it while blood flow is paused.
  4. The surgeon opens the kidney along the low-blood-vessel plane identified above, giving direct access to the stone-filled drainage system.
  5. The stone is removed, sometimes with a small incision to widen a narrowed drainage channel if needed.
  6. An X-ray is taken during surgery to confirm no fragments are left behind.
  7. The internal drainage system and the kidney itself are stitched closed, and blood flow to the kidney is restored.
  8. A drain — and sometimes a temporary internal stent — is left in place to help urine flow and healing.

Immediately after surgery: You’ll wake up with a surgical drain near the incision and possibly a temporary ureteral stent. Pain control, early walking, and monitoring for bleeding or infection are the focus of the first 24–48 hours.

Session duration
2.5–3.5 hours
recorded for this treatment
Cost verify
$15000–$40000
indicative range
Anesthesia
General
recorded for this treatment
Remember: The exact steps, duration and preparation can vary with your indication, health and care setting. Confirm the current plan with your treating team.

Benefits

The trade-off of a bigger operation is that it can finish the job in one go, which matters most for the largest, most complex stones.

  • Can achieve complete stone clearance in a single operation, even for very large or branching staghorn stones — reported stone-free rates in case series range from 80–100%.
  • Gives direct visual and physical access to the stone and the kidney’s internal anatomy, useful when structural problems (like a narrowed drainage point) need to be corrected at the same time.
  • May avoid the multiple repeat procedures sometimes needed with keyhole techniques for very large or complex stones.

Risks & side effects

The treatment has risks and trade-offs to discuss with your care team. The information below comes from this treatment’s data.

  • Significant bleeding, occasionally requiring a blood transfusion.
  • Infection, including at the incision site or within the urinary tract.
  • Risks associated with general anaesthesia.
  • A longer, more visible incision and a longer recovery than keyhole alternatives.
  • A higher chance of incisional hernia at the surgical site later on.

Bleeding, infection and anaesthesia-related issues are the main concerns; risks are minimised by careful patient selection and experienced surgical teams.

Who it may not suit: These are general cautions, not a personal verdict. A qualified clinician must assess your full medical picture before recommending or delaying treatment.

What happens during & after

Most patients stay in hospital for several days to about a week. The drain is usually removed before discharge; a stent, if placed, is typically removed by your urologist within 1–4 weeks in a short outpatient visit.

Possible complications

Beyond the risks above, a smaller number of patients face more serious complications that affect kidney healing or function directly.

  • Temporary or, rarely, lasting reduction in kidney function.
  • Urine leakage from the surgical repair site.
  • In rare, severe cases, damage significant enough that the kidney cannot be saved.
  • Residual stone fragments that need a follow-up procedure.
  • General surgical complications: blood clots, wound-healing problems, chest infection from prolonged bed rest.

This is general educational information, not a personal risk assessment. Your own risk profile depends on your health, kidney function and stone complexity — discuss it directly with your urologist.

Remember:

New or severe symptoms require prompt medical advice. Do not wait for a routine appointment if you feel seriously unwell.

Recovery

What to expect:

  • Hospital stay: Typically several days up to about a week.
  • Drain removal: Before you leave hospital, once drainage has settled.
  • Stent removal (if placed): Usually within 1–4 weeks, in a quick outpatient appointment. Some discomfort or urinary urgency while the stent is in place is normal.
  • Return to light activity: Gradual, guided by your surgical team.
  • Full recovery: Most guidance points to roughly 4–6 weeks before resuming normal activity, longer than the days-to-two-weeks typical after keyhole stone procedures.
  • Follow-up: Imaging and check-ups to confirm the kidney is healing and to watch for new stone formation.

When to contact your doctor urgently:

Call your urology team right away if you notice:

  • Sudden or worsening flank or incision pain that isn’t controlled by your prescribed medication.
  • A fever over 100.4°F (38°C).
  • Persistent nausea or vomiting.
  • Redness, swelling, or discharge at the incision site.
  • Difficulty breathing, chest pain, or a cough that doesn’t resolve.

If any of these feel like an emergency, seek emergency care immediately rather than waiting for a callback.

Specialists for Open stone surgery (anatrophic nephrolithotomy)

Specialists linked to this treatment in the KidneyGlobal directory. Review credentials and confirm availability directly before booking.

Verified specialists

2 specialists match this treatment
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Prof. Piotr Radziszewski
4,8
★★★★★
234 reviews
🎗Urology · Urologic Oncology · Robotic Surgery · Functional Urology
🏅25 years of experience
🏥Massachusetts General Hospital · Cleveland Clinic
📍Warsaw, Mazovian, Poland · Telemedicine · Accepting new patients
🗣English · French · Polish · Russian
Dr. Michael Chen
4,9
★★★★★
198 reviews
🎗Urology · Urologic Oncology · Robotic Surgery
🏅12 years of experience
🏥Massachusetts General Hospital · Cleveland Clinic
📍Los Angeles, CA, United States · Telemedicine · Accepting new patients
🗣Cantonese · English · Mandarin

Clinics offering Open stone surgery (anatrophic nephrolithotomy)

Verified kidney centres linked to this treatment in the KidneyGlobal directory.

Good questions

Most Common Questions

Is open stone surgery still done today?

Yes, but rarely. It has been replaced as the default treatment by percutaneous nephrolithotomy (PCNL), ureteroscopy and shockwave lithotripsy. Surgeons now use it mainly for complex staghorn stones that other methods can't clear, or when a patient's anatomy or health makes keyhole surgery too risky.

Is anatrophic nephrolithotomy the same as open stone surgery?

Anatrophic nephrolithotomy is a specific, precise technique for open stone removal. "Open stone surgery" is the broader term and can also include simpler open procedures like pyelolithotomy or ureterolithotomy.

Is there a minimally invasive version of this operation?

Some centers now perform anatrophic nephrolithotomy laparoscopically or with robotic assistance in carefully selected patients, which can mean a smaller incision. This isn't available everywhere and depends on surgeon experience and your anatomy.

What's the success rate for clearing the stone completely?

Case series report stone-free rates of roughly 80–100%, generally higher than single sessions of shockwave lithotripsy or PCNL for the same type of complex, large staghorn stones — though direct comparisons depend heavily on stone complexity.

Can the stone come back after surgery?

Yes. Any kidney stone treatment removes the existing stone but doesn't change your underlying tendency to form stones. Metabolic evaluation and prevention (fluid intake, diet, and sometimes medication) matter after any stone surgery.

How long until I can go back to work?

Most patients need around 4–6 weeks before resuming normal activity, though desk-based work may be possible sooner and physically demanding work will take longer. Your surgeon will tailor this to your job and how your recovery is progressing.

Sources

  1. Surgical Management of Stones GuidelineAmerican Urological Association / Endourological Society
  2. Summary of AUA (2016) and EAU Urolithiasis Guideline positions on open/laparoscopic stone surgeryScielo (Revista da Associação Médica Brasileira)
  3. Anatrophic Nephrolithotomy (technique description, Urology, 2001)Assimos DG
  4. Anatrophic Nephrolithotomy in the Management of Large Staghorn Calculi — A Single Centre Experience (Journal of Clinical and Diagnostic Research, 2017)Keshavamurthy R, et al.
  5. Indication to Open Anatrophic Nephrolithotomy in the Twenty-First Century: A Case Report (Case Reports in Urology, 2012)Bove AM, et al.
  6. Open Surgery for Kidney Stones (patient health encyclopedia)Kaiser Permanente