
Autotransplantation of the kidney
Kidney autotransplantation removes your kidney, repairs it outside your body if needed, and reimplants it in a new site — usually the pelvis — so you keep your own kidney without ever needing anti-rejection medicine.

Briefly about this treatment
Indications
Long-standing kidney pain and bleeding that hasn't responded to medication (loin pain–hematuria syndrome), Nutcracker syndrome, a renal artery aneurysm or other vascular problem that can't be fixed with a stent, a badly damaged ureter, or a tumour in your only working kidney.
Risks
Bleeding, infection, and problems with the reconnected blood vessels or ureter. Risks are minimised by careful patient selection and experienced teams.
Pre-procedure
Standard blood work, imaging of the kidney and its blood vessels, an anaesthesia consultation, and fasting per protocol before surgery.
Follow-up
Scheduled clinic visits at about 2–3 weeks (stent removal), then 1, 4 and 12 weeks; long-term monitoring of kidney function and pain relief.
What is Autotransplantation of the kidney? An expert explains
Kidney autotransplantation (also called renal autotransplantation) is a specialized surgery reserved for a small number of complex kidney problems that can’t be fixed with the kidney left in its normal position. Surgeons remove the affected kidney, and — if it needs vascular or ureteral repair — work on it on a „back table” using cold preservation, much like preparing an organ for a standard transplant. The repaired kidney is then reimplanted, typically into the pelvis near the iliac blood vessels and bladder, and the ureter is reconnected. A kidney transplant from a donor and a kidney autotransplant use a similar surgical technique, but they are not the same procedure: a donor transplant needs lifelong immunosuppression to prevent rejection, while an autotransplant does not, because your immune system already recognizes the kidney as yours (Penn Medicine; University of Colorado). It’s a rare operation, performed at a limited number of specialized centers, most often by a multidisciplinary team of transplant surgeons, urologists, interventional radiologists and nephrologists working together (UCHealth).
Signs it may be time for Autotransplantation of the kidney
Watch for patterns like these, which your care team weighs together with your test results — no single symptom on its own means you need this surgery:
- Ongoing flank or loin pain with visible or repeatedly detected blood in your urine
- Pain that hasn’t eased with medication, nerve blocks or other standard treatments
- Pelvic or flank pain linked to a known vein-compression problem (Nutcracker syndrome)
- Pain from recurring kidney stones that standard stone treatment hasn’t controlled
- A known renal artery or ureter problem your team says can’t be fixed with a stent or repaired in place
These are the conditions linked to this treatment in the directory. Your clinician decides whether treatment is appropriate using your symptoms, examination and test results.
- Chronic Kidney Disease (CKD) — Progressive, long-term loss of kidney function.
- End-Stage Renal Disease (ESRD) — Final stage of kidney failure requiring dialysis or transplant.
- Polycystic Kidney Disease (PKD) — Inherited disorder with fluid-filled cysts in kidneys.
Remember: These entries are not a diagnosis or a treatment recommendation. Discuss your symptoms and test results with a qualified clinician.

When to consult a specialist
A single episode of flank pain usually isn’t cause for alarm — most kidney pain has a simpler explanation, and a blood or urine test can often point your doctor in the right direction early on. But if the pain keeps coming back, doesn’t ease with the usual treatments, or comes with visible blood in your urine, it’s worth getting checked rather than waiting it out. Use our find a specialist tool to connect with a nephrologist or urologist who can review your symptoms and test results and tell you whether autotransplantation — or a simpler option — is right for you.
How a session works
Kidney autotransplantation is done under general anesthesia and usually takes several hours. The exact steps depend on why you need it, but a typical sequence looks like this:
- Pre-surgery workup. You’ll come in a day or two beforehand for blood tests, imaging and an EKG, and your team will confirm the plan with you (UW Health).
- Removing the kidney (nephrectomy). The surgeon detaches the kidney and its ureter from their original position, through an open incision or, increasingly, a minimally invasive laparoscopic or robot-assisted approach (University of Colorado).
- Cooling and back-table repair. The kidney is flushed with cold preservation solution and, if needed, repaired outside the body — the same way a donor kidney is prepared before a standard transplant.
- Reimplantation. The kidney is placed in its new position, typically the pelvis near the iliac vessels; the artery and vein are reconnected, and the ureter is reattached to the bladder with a temporary stent (UCHealth).
- Checking function. The team confirms the kidney is well perfused and producing urine before closing.
Benefits
This surgery exists to save a kidney that would otherwise be removed or left to fail — and that shapes everything it offers.
- Preserves kidney function instead of removing the kidney outright — the main reason this surgery exists (UCHealth)
- No immunosuppression needed. Because it’s your own tissue, there’s no rejection risk and no lifelong anti-rejection medication, unlike a donor kidney transplant (Penn Medicine)
- Meaningful pain relief for some conditions. For loin pain–hematuria syndrome specifically, published case series from specialized centers report substantial, often long-lasting pain improvement in carefully selected patients. Results vary by center and diagnosis — these are study outcomes, not guarantees for any individual.
- You keep two kidneys (assuming your other kidney is healthy), rather than living with one after a nephrectomy.
Risks & side effects
The treatment has risks and trade-offs to discuss with your care team. The information below comes from this treatment’s data: bleeding, infection, vascular access issues. Risks are minimised by careful patient selection and experienced teams.
- Bleeding requiring transfusion, and blood clots
- Infection, including at the incision site or around the kidney
- Anesthesia-related risks
- Narrowing of the reconnected ureter (stricture), sometimes requiring a further procedure
- Leakage at the ureter-to-bladder connection
- Narrowing or clotting of the reconnected blood vessels, which can threaten the kidney’s blood supply
- Temporary or, rarely, permanent reduction in the kidney’s function, and in rare cases loss of the autotransplanted kidney
Who it may not suit: These are general cautions, not a personal verdict. A qualified clinician must assess your full medical picture before recommending or delaying treatment.

What happens during & after
In hospital (days 0–7). After surgery, you’ll be monitored closely for how well the repositioned kidney is working — through urine output, blood tests and imaging — and for signs of bleeding or infection. Most people are in the hospital for about three to seven days (UCHealth; UW Health).
First few weeks at home. You’ll need to stay near the treatment center for follow-up visits and have someone available to help you around the clock until your first post-surgery check, usually about two to three weeks out. That visit typically includes lab work and removal of the ureteral stent placed during surgery (UW Health).
Weeks to months. Most people gradually return to normal activity over several weeks to a few months, with continued follow-up testing to confirm the kidney is working well and pain (if that was the reason for surgery) is improving.
Possible complications
Most recoveries go smoothly, but contact your care team promptly if you notice:
- Fever, spreading redness, or drainage at the incision site (possible infection)
- Sudden increase in pain, or new flank pain (could signal a vascular or ureteral problem)
- A significant drop in urine output
- Swelling, warmth or pain in a leg (possible blood clot)
- Persistent nausea, vomiting, or inability to keep fluids down
A minority of people need a second procedure during recovery — for example, to treat a ureteral stricture — even after a technically successful operation. This doesn’t necessarily mean the autotransplant failed; it’s part of why close follow-up matters in the weeks after surgery. This is general guidance, not a substitute for your care team’s specific instructions.
New or severe symptoms require prompt medical advice. Do not wait for a routine appointment if you feel seriously unwell.
Recovery
Recovery from kidney autotransplantation happens in three stages. In the hospital, your team watches urine output, blood tests and imaging to confirm the kidney is working and there’s no bleeding or infection — typically three to seven days. Once home, you’ll stay near the treatment center for close follow-up, with someone available around the clock, until your first check at about two to three weeks, when the ureteral stent is usually removed. Over the following weeks to months, most people gradually return to normal activity, with repeat testing to confirm the kidney’s function and, where pain was the reason for surgery, that it’s easing. Full recovery timelines vary by age, overall health, and whether surgery was open or minimally invasive.
Specialists for Autotransplantation of the kidney
Specialists linked to this treatment in the KidneyGlobal directory. Review credentials and confirm availability directly before booking.
Verified specialists



Clinics offering Autotransplantation of the kidney
Verified kidney centres linked to this treatment in the KidneyGlobal directory.




Most Common Questions
Is kidney autotransplantation the same as a kidney transplant?
No. A kidney transplant uses a donor organ and requires lifelong immunosuppression. In an autotransplant, surgeons move and repair your own kidney, so rejection isn't a concern (Penn Medicine).
How rare is this procedure?
It's uncommon. Most published experience comes from small case series at specialized centers rather than large trials, because the conditions it treats are themselves rare.
Will I still have two working kidneys afterward?
If your other kidney is healthy, yes — autotransplantation moves and repairs one kidney; it doesn't remove your second kidney (UCHealth).
Does it definitely cure my pain?
Many people get substantial pain relief, and some published series report high improvement rates in carefully selected patients, but outcomes vary by diagnosis and center. Talk to your surgical team about what's realistic for your case.
How long will I be in hospital?
Most people stay about three to seven days so the team can confirm the kidney is working well and watch for bleeding or infection (UCHealth; UW Health).
Can I live a normal life afterward?
Most people gradually return to their normal activities over weeks to a few months. Long-term outlook depends on the reason for surgery and your overall kidney health — ask your surgical team what to expect in your case.
Sources
- Kidney Auto TransplantPenn Medicine
- Renal AutotransplantUCHealth
- Renal Autotransplant: End Your Pain and Restart Your LifeUW Health
- Renal Autotransplant (Transplant Surgery)University of Colorado School of Medicine (CU Anschutz)
- Clinical advances in kidney autotransplantation: a reviewBMC Surgery (2025)
- Experience with Renal Autotransplantation: Typical and Atypical IndicationsAdvances in Urology (PMC)